ICBO 2026

17th International Conference on Biological and Biomedical Ontology

"Semantic Awareness in the Age of Generative AI"

July 15–17, 2026

Washington Hilton, Washington D.C. (Co-located with ISMB 2026)  |  Online Participation Available

Theme of ICBO 2026

The International Conference on Biological and Biomedical Ontology (ICBO) is a premier annual conference series covering the development and application of ontologies for biological and medical domains.

The emergence of Generative AI (GenAI) is fundamentally altering the landscape of biomedical research, knowledge integration, and scientific communication. However, the rapid acceleration of data generation does not inherently lead to improved scientific understanding. As AI systems increasingly mediate the synthesis of knowledge, the requirements for semantic rigor, ontological grounding, and data trustworthiness become more paramount.

ICBO 2026 invites contributions exploring the critical role of ontologies and semantic technologies (including formal semantics based Knowledge Graph) in developing trustworthy, interpretable, and AI-ready ecosystems. We welcome research across the domains of biology, medicine, health, behavioral science, environmental health, and food systems.

While GenAI offers powerful capabilities for data processing and synthesis, it serves as a complement to, not a replacement for, formal semantics, logical consistency, and community-curated knowledge structures.

Important Dates at a Glance

Milestone Deadline
Early Bird Registration May 30, 2026 June 5, 2026 (Extended!)
Workshop & Tutorial Proposals March 30, 2026
Direct-to-Journal Track April 15, 2026
Main Conference Papers May 1, 2026
Posters & Software Demos June 1, 2026 June 12, 2026 (Extended!)
Conference July 15–17, 2026

Call for Submissions & All Deadlines


Keynote & Invited Speakers

Keynote Speaker

Richard Scheuermann, NIH/NLM Toward a complete lexicon of cell types in the biomedical literature

Invited Speakers

Reed Shabman NIAID Towards an AI-Ready Data Ecosystem: How Ontologies Support Metadata Findability and Interoperability in the NIAID Data Ecosystem Discovery Portal
Lynn Schriml UMD Disease data standardization landscape: role of ontologies, NER and AI in biocuration
Maria Shatz NIH/NIEHS Environmental Health Language Collaborative: Data standards and ontologies for Exposomics
Rajkumar Cholan NIH/NLM
Birgit Meldal Pfizer

Topics of Interest


Accepted Workshops

The VDOS workshop explores innovative solutions and challenges in the ontological representation of drugs and vaccines, covering administration, immune responses, adverse events, and drug interactions. This year's focus extends to how AI and large language models can revolutionize ontology studies, enhancing literature mining, meta-analysis, and complex data interpretation.

Journal Paper Submission: May 15, 2026 EasyChair Submission: June 1, 2026 Notification: June 15, 2026 Workshop: July 2026 (co-located with ICBO 2026)

Workshop Homepage

Full-day Workshop

Cell Type Knowledge in the Age of Foundation Models and Agentic AI: Bridging ML, Omics, Literature, and Ontologies

This workshop brings together researchers working at the intersection of single-cell and spatial omics, agentic AI, and biomedical ontologies to explore how foundation models and knowledge graphs can scale cell type curation, improve ML model interpretability, and bridge data-driven cell phenotypes with curated classical knowledge.

Paper Submission: TBD Workshop: July 2026 (co-located with ICBO 2026)

Accepted Talks

# Title Primary Author/Speaker
1 Investigating the use of an ontology for grounding LLMs: Using GraphRAG with the Foundational Model of Anatomy Melissa Clarkson
2 The ROBOKOP Biomedical Knowledge Graph System: Leveraging Ontologies for Data Normalization, Integration, and Query Karamarie Fecho
3 Frontier LLM-based agents can overcome the ontology curation bottleneck for natural phenotypes James Balhoff
4 Consistent but Incorrect: Detecting Discrepancies in Ontologies Christian Kindermann
5 Evidencell - an agentic research assistant for the Cell Ontology David Osumi-Sutherland
6 ACCELERATE-BASSO: Advancing Behavioral and Social Science Research through Ontology Best Practices Cui Tao
7 OnTEPT: A multimodal OWL ontology for post-traumatic stress disorder Diego M. López

Domains of Interest

Submissions are encouraged within, but not limited to:

  • Biomedical and biological research
  • Clinical and public health data integration
  • Physical and mental wellness and behavioral science
  • Environmental health, food systems, and sustainability
  • Regulatory science and policy-making

Community

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Sponsors


Contact Information

Please direct all questions to Asiyah Yu Lin — ontology.world@gmail.com